In-vivo CAR-T Cell Therapy: New Frontier in Cancer Treatment
Chimeric antigen receptor T-cell (CAR-T) therapy transformed oncology by paving the path for harnessing patients’ own cells to treat B-cell lymphomas, leukemias, and other hematological malignancies. Traditionally, CAR-T cell therapy for cancer relied on ex vivo processes, where a patient’s T-cells are extracted, genetically reprogrammed in an external medium to express synthetic receptors targeting cancer […]
Technology Overview & Start-up Scouting for Development of Allogeneic iPSCs
A clinical-stage biopharmaceutical company approached Stellarix to get a technology and innovation overview in the allogeneic iPSCs segment. Our strategic intelligence helped the client gain a future outlook on allogeneic iPSCs development with HLA/MHC knockdown, reforming its market and business strategy. Client Background: Clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent […]
Winning in the Margins: Commercial Strategy for New Entrants in the Adalimumab Autoinjector Market
Overview The adalimumab autoinjector market is becoming increasingly competitive, with multiple biosimilar manufacturers challenging established brands through aggressive pricing, product innovation, and evolving market access strategies. With 10 biosimilar competitors examined and discount levels reaching up to 85% versus Humira in the research, the commercial challenge extends beyond affordability. New entrants must differentiate through formulation, […]
Technology Overview – Active Drug Delivery System
A leading healthcare company sought our assistance to embrace innovative solutions in drug delivery. Our strategic intelligence equipped them with actionable insights to accelerate their innovation pipeline, restructure their R&D efforts, make well-informed investment decisions, and establish strategic partnerships. Client Background: The client is an established healthcare leader, committed to advancing drug delivery through innovative […]
Beyond Appetite: Discovering Hidden Opportunities in the GLP-1 Era
In just a few short years, GLP-1 receptor agonists have transformed from specialized diabetes medications to household names. Drugs like Ozempic, Wegovy, Mounjaro, and Zepbound dominate headlines, social media discussions, and increasingly, medicine cabinets across the country. While their weight loss benefits have captured public attention, the true revolution extends far beyond the bathroom scale. […]
Trump’s Pharma Tariffs: Risks, Impact & Strategy
This is not a recent development; it started with the end of Trump’s first term. During the last quarter, executive orders were issued to cut down the costs of medicines. However, the federal court dismissed the motion, citing that this motion didn’t involve public opinion. The Biden administration also attempted it with the IRA when […]
IP Landscape- Lipid Nanoparticles for Biomolecules Delivery
A global pharmaceutical leader partnered with Stellarix to gain strategic insights into lipid nanoparticle (LNP) systems for biomolecule delivery. With LNPs emerging as a critical platform for mRNA, siRNA, and CRISPR-based therapeutics, recognized and regulated by the FDA—our case study mapped key components, formulation strategies, and advanced manufacturing practices. Client Background: The client is a […]
Bispecific Antibody-Drug Conjugates: Clinical Development and Future Directions
In the last decade, ADCs have been an emerging class of medical modalities to treat cancer by combining potent anti-cancer medicines (i.e., payloads) with monoclonal antibodies that deliver cancer medicines to the target cells. According to the market reports, the global ADC request size was valued at around 11.84 billion USD in 2024 and is […]
Automation in Bioprocessing
Bioprocessing involves culturing microbes or living cells to produce essential and valuable substances, such as pharmaceutical compounds. In the field of biopharmaceutical manufacturing, it is imperative that these bioprocesses are optimized for sustainable and innovative solutions. Integrating automation in these processes will increase efficiency, reduce human errors, and improve accuracy. Bioprocess automation is governed by […]
Circular RNA – Exploring New Potentials Beyond the Loop
Circular RNAs (circRNAs) are a specific group of non-coding RNAs that are present in a structural covalently closed loop and do not exhibit distinct five caps and 3poly (A) tails like linear RNAs. It was first identified as a structural element in viroids in 1976, where circRNAs lay unnoticed for nearly two decades until they […]